The impact of age, gender and fasting blood glucose on serum lipid profile at tertiary care hospital: a retrospective study.

BACKGROUND AND AIM: This relatively large retrospective study explores the impact of age, gender and fasting blood glucose level on lipid profile. It has been known that many factors could influence the lipid profile. It is crucial to investigate these relationships as dyslipidemia has been linked to many critical diseases such as cardiovascular disease.   Methods:Data of 3115 individuals were collected include the age, gender, total serum cholesterol, high-density lipoprotein (HDL), low-density lipoproteins (LDL), triglyceride (TGL) and fasting glucose levels at King Fahad Military Medical Complex's Clinical Chemistry Laboratory, Dhahran, from January 2019 to July 2019.   Results: The results shows that people who were 65 years or older had significant association with total cholesterol (p<0.001), LDL (p-value= 0.001) and triglycerides (p-value= 0.001). Regarding gender,  women, in general, are 1.2 times more likely to have hypercholesterolemia than men. Diabetes was significantly associated with all lipid profile parameters.   Conclusions: There is a variable association between lipid profile with age, gender, and fasting glucose.

Molecular epidemiology of SEN virus among blood donors and renal dialysis patients.

BACKGROUND AND PURPOSE: The SEN virus (SEN-V) is a single-stranded circular, non-enveloped DNA virus that has been linked to blood transfusion and is thought to be a major cause of post-transfusion hepatitis. The two SENV types, SENV-H and SENV-D, are non-A to E hepatitis viruses  in those who are infected. The purpose of this study is to find out how common SENV and its variations are among renal dialysis patients and healthy blood donors. METHODS: The study used a cross-sectional design, with 300 blood samples collected from KFMMC patients, 150 from healthy blood donors and 150 from renal dialysis patients, between January 2019 and January 2021. The samples were screened for the presence of SENV-D and SENV-H. using nested PCR. RESULTS: Molecular analysis of the SEN virus revealed that 9.3% of the samples (14 out of 150) tested positive for SEN virus infection in renal dialysis patients. The data from healthy donors revealed that 10% of the samples tested positive for the SEN virus (15 out of 150). CONCLUSIONS: The presence of SEN-V in healthy blood donors and renal dialysis patients demonstrates the virus's blood-borne nature and emphasizes the dangers of blood-borne transmission.